Academic Calendar-B. Pharm. & M. Pharm. 2024-2025 Click here B.Pharm. Vacant Quota Admission - 2024-25 Click here B.PHARM. MANAGEMENT QUOTA/ NRI SPONSORED SEATS ADMISSIONS YEAR: 2024-2025 Click here M.Pharm. Vacant Quota Seats Admission 2024-25 Click here B.PHARM. ADDITIONAL VACANT QUOTA SEATS ADMISSIONS YEAR: 2024-2025 Click here
Academic Calendar-B. Pharm. & M. Pharm. 2024-2025 Click here B.Pharm. Vacant Quota Admission - 2024-25 Click here B.PHARM. MANAGEMENT QUOTA/ NRI SPONSORED SEATS ADMISSIONS YEAR: 2024-2025 Click here M.Pharm. Vacant Quota Seats Admission 2024-25 Click here B.PHARM. ADDITIONAL VACANT QUOTA SEATS ADMISSIONS YEAR: 2024-2025 Click here
Pharmacology
The Pharmacology Department is a very dynamic department comprising of experienced and young dynamic staff with diversified expertise in field of Drug Discovery and Development.
It is a Pre-clinical contract research organization (CRO) providing in vitro and in vivo efficacy studies for endocrinal, inflammatory, neurology and toxicology fields. Our approach and capability is aligned to a mechanistic development program. that deliver important mechanistic data on efficacy with reproducibility, efficient timelines, and quality reporting. Capability to develop new models to fulfil unmet needs We have also the expertise to prepare a protocol for clinical studies viz. Bioavailability and Bioequivalence studies and Drug Master File/Dossier for excipients and/or drug substance according to different regulatory agencies.
Spacious laboratories with adequate equipment capable of providing the much needed technical support for teaching and research. Laboratories are equipped with sophisticated instruments used for development and evaluation of Test Substances (Approx. cost of instruments: Rs. 35,44,191/--).State of the art CPCSEA approvedc Animal Housing Facility constructed as per CPCSEA standards and it can accommodate 600 plus rats and 1000 plus mice.
Department received funding from government agencies like AICTE, GUCOST, ICMR etc. Till date grant received of Rs.11,35,000/-, accomplished several industry sponsored research projects and consultancy projects worth more than 15 Lacs.
More than 107 M. Pharm students and more than 10 Ph.D. scholars have been awarded till date. Many prestigious prizes from various conferences and seminar for BEST M.PHARM THESIS and BEST RESEARCH WORK Active international and national presence of faculties and students in terms of publications and presentations (International and National Publication: More than 100, International and national presentation: More than 200).
Laboratory
- Anatomy & Physiology Laboratory: This lab is mainly occupied by B. Pharm Sem- I & II students for practicals related to Human Anatomy & Physiology courses. In this lab, students perform experiments of hematology, urine analysis. Faculties teach the anatomy and physiology of various systems using charts and models.
- Pharmacology Laboratory: This well-equipped laboratory helps to train B.Pharm students in practical studies of Pharmacology & Toxicology and Clinical Pharmacy. B. Pharm students carry out a variety of animal experiments i.e. pD2 value, pA2 value, bioassay of drugs, screening and evaluation of drugs, and clinical experiments i.e. prescription audit, case studies, pharmacotherapeutics, laboratory data interpretation, and so on. The advanced pharmacology laboratory is specially designed to carry out animal model experiments for analgesic, anti-histaminic, anti-pyretic, anti-hepatotoxic, anti-ulcer, anti-inflammatory activity, antidiabetic, antihyperlipidemic, anti-stroke, antiasthmatic, and so on.
- Advanced Pharmacology Laboratory: This is the core laboratory of the pharmacology department and it is mainly used by M. Pharm students. This laboratory comprises a couple of sophisticated instruments. M. Pharm students carry out different experiments of Cellular & Molecular Pharmacology, Advanced Pharmacology & Toxicology, Pharmacometrics, and evaluation of drugs.
- Animal House Facility: Central Animal Housing Facility is constructed as per CPCSEA guideline and registered with CPCSEA and its registration number is 197/PO/c/2000/CPCSEA. It comprises ample room which can accommodate more than 600 rats, 1000 mice, and 20 Guinea pigs.
Research
Experienced faculty members of the department have identified the core areas of research in pharmacology and toxicology facet for Ph.D. and MPharm dissertation projects.
In-vitro studies:
- Aldose Reductase inhibition using rats lens
- PPAR-gamma agonistic assay
- Anti-Stroke using PC12 cell line
- Antidiabetic activity
- Cytotoxicity studies
- Antioxidant activity
- Enzyme inhibitory activity
- Chromosomal aberration assay
- Ames test
- Micronucleus assay
- Hepatoprotective activity
- Antiobesity activity
In-vivo studies:
- Inflammation disease models: - General models of inflammation - Allergic asthma in vivo model - Arthritis in-vivo inflammation models - Inflammatory Bowel Disease (IBD) in-vivo models.
- CNS models: - Cognition enhancer - Antidepressant - Anti-anxiety - Sedative/hypnotics - Anti convulsant - Anti psychotics.
- Pain models: - Nociception pain models using a hot plate and tail-flick models - Neuropathic pain model- diabetic neuropathy - Inflammatory pain model- carrageenan and formaldehyde.
- Ischemia-reperfusion injury model: - stroke and Myocardial Ischemia.
- Endocrine disease model: - single dose of STZ treated Type-I diabetes model - STZ+ HFD model for Type-II diabetes - HFD model for obesity.
- CVS models: -Coronary artery ligation model for myocardial infarction - DOCA-salt-induced hypertension in rats - Fructose induced hypertension in rats - Two Kidney One Clip model for hypertension.
- Toxicity studies: - Single, repeated dose toxicity study - Dermal Irritation toxicity study - Biocompatibility study - Mutagenicity - Genotoxicity